【摘要】Itch (also called pruritus) is an unpleasant somatosensation that evokes a desire or reflex to scratch in humans and other mammals [1].Itch is now considered to be a unique sensory modality that is encoded by a labeled line that has genetically distinguishable neurons in the peripheral and central nervous systems [1].Acute itch evokes scratching that may help to remove potentially harmful irritants from the skin,which is believed to be evolutionarily important
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